10 Best Formulas for Reflux Reviewed in 2024
No one likes an upset tummy. For babies especially, indigestion can be a big problem. Gastroesophageal reflux (also called GER or just plain reflux) can cause infants to be fussy when it comes to eating and can lead to being unable to hold down the important nutrients in their formula. Often, this issue arises due to a sensitivity to lactose. Usually, this means an inability to properly digest milk proteins can make babies gassy and nauseous. Thankfully, many companies have addressed this problem through formulas that are specifically designed to be gentle on baby’s stomach. The following ten baby formulas are all targeted towards little ones with sensitive stomachs. They pack all the important nutrition in, with none of the gassiness, fuss, or crying. Make mealtime easier on everyone with the best formulas for reflux.
In a Hurry? The test winner after 44 hrs of research

Designed to be very similar to breast milk
Does not have artificial growth hormones
Reduces spit-up, gassiness, and fussiness in babies
Is the #1 brand recommended by doctors
Has the same nutrition found in breast milk












10 Best Formulas for Reflux Reviewed
1. Similac Pro-Advance


Designed to be very similar to breast milk
Does not have artificial growth hormones
Reduces spit-up, gassiness, and fussiness in babies
Is the #1 brand recommended by doctors
Has the same nutrition found in breast milk
Some did not like the smell of the formula
A few complaints about the color of the liquid
Having the same nutrition that is found in breast milk such as vitamin E, lutein, and DHA, Similac Pro-Advance Infant Formula reduces spit-up, gassiness, and fussiness in babies. It does not have any artificial growth hormones in it and is the top choice of parents.
Read moreIngredients
Doctors recommend it as the number one brand to support the immune system of babies. This product is a 48-count package of two-ounce fluid bottles that are designed to be very similar to breast milk. This trusted reflux formula brand has nourished generations of infants, as it provides support for the baby’s eye and brain development.
Brand
If you can believe it, Similac’s roots trace back to 1903 when the Moores and Ross milk Company was founded. Two decades later they created the first commercial milk-based baby formula. Since 1925, Similac has been one of the top names on the market and with good reason.
Effectiveness
To reduce problems of reflux in babies, this is a wonderful formula that will work. It will reduce spit-up, gassiness, and fussiness in infants quickly.
2. Similac Advance with Iron


#1 brand recommended by hospitals and doctors
Loved and trusted by parents
Does not contain genetically-engineered ingredients
Supports eye health and brain development
Reduces gassiness, spit-up, and fussiness
It may be hard to open
Some people received damaged packages
Similac is an obvious leader when it comes to infant formulas, as even our list proves. This is another winning Similac product that has customers so satisfied with its performance. The Advance Infant Formula with Iron also does a fabulous job at reducing reflux in your child, as it decreases gassiness, spit-up, and fussiness.
Read moreIngredients
This terrific formula does not contain any ingredients that were genetically engineered. Infants do not need ingredients that have been altered because they must have the best start in life.
Brand
Just because Similac has been around for nearly a century doesn’t mean it’s stale or behind-the-times. This company works to constantly be using the most up-to-date nutrition information and innovative ideas so families don’t fall behind.
Effectiveness
Reducing reflux for your baby is as easy as using this wonderful infant formula from Similac. It will prevent the problem from occurring with special complete nutrition.
3. Earth's Best Organic Iron


Is nutritionally complete and easy to digest
Made with non-GMO ingredients
Reduces gas and fussiness
Is a gentle formula that is easy to digest
Is the number one organic infant formula in the U.S.
Has corn syrup solids in the ingredients
Made some babies have harder stools
Earth’s Best Organics Infant Powder Formula has the most reviews online of any other leading brand. It reduces gas and fussiness in babies, relieving them of common reflux problems. Containing iron, lutein for eye health, and probiotics for immunity health, this wonderful diet is a gentle formula that is easy to digest.
Read moreIngredients
This is the best organic brand of infant formula in the U.S. it is made with non-GMO ingredients and does not contain harmful synthetic chemicals.
Brand
Earth’s Best is a product of The Hain Celestial Group. This company is dedicated to providing wholesome and pure nutrition to babies and has been in the business since 1985. Earth’s Best utilizes hand-picked organic fruits and vegetables and believes in environmental responsibility as well as quality products.
Effectiveness
Gentle formulas like this one are easy to digest and reduce fussiness and gas. Eliminating reflux is important in a healthy happy baby.
4. Kabrita Non-GMO Goat Milk


Decreases reflux and spitting up
Does not contain GMO ingredients
It may be good for a baby that is sensitive to cow’s milk
Has a smell and taste that is fresh, sweet, and mild
Is nutritionally complete
Caused constipation in some babies
Did not relieve the gas for a few infants
To decrease reflux and spitting up for your baby, try this Kabrita product of Non-GMO Goat Milk in a powder form. Protein from goat milk forms a looser softer curd in the gut than protein from cows, and this product meets the infant formula nutritional requirements.
Read moreIngredients
With twenty-two minerals and vitamins in this baby diet, complete nutrition is simple and easy. It has all the nutrients that an infant needs to be healthy and happy.
Brand
Kabrita is innovative in more than one way. Dedicated entirely to goat-milk products, this company is run entirely by women. Led and backed by moms, Kabrita is also a proponent of education, transparency, and encouraging communication.
Effectiveness
Sometimes infants cannot tolerate cow’s milk and need another formula that can be digested. This product of goat’s milk is milder and will decrease gas, reflux, and spitting up.
5. Enfamil Nutramigen Infant


Is lactose-free and hypoallergenic
Provides relief from gas, reflux, and spitting up
Will manage colic with the first feeding
Proven to reduce future challenges of allergies
Supports the digestive health of the baby
Some did not like the cornstarch ingredient
A few babies did not like the formula
Enfamil is the number one formula that pediatricians recommend, and it is such a trusted brand that we feature four of their top products on this page that help fight reflux in babies. This formula is lactose-free and hypoallergenic.
Read moreIngredients
Relief from gas, reflux, and spit-up is a huge relief for parents. Formulas such as this one strive to decrease this from occurring in infants so they can maintain their proper nutrition levels.
Brand
Enfamil boasts being a company “exclusively focused on nutrition.” They study up on food science and wellness even before creating their formulas. These products are modeled after breastmilk in as many ways as scientifically possible to provide your baby with the nutrients they need.
Effectiveness
It provides relief from gas, reflux, and spitting up of formula. Proven to reduce future challenges of allergies, this fantastic diet will manage colic with the first feeding. It helps infants consume a milk protein without having an allergic response and supports the digestive health of the baby. This Enfamil diet provides complete nutrition for the first year of life for your child.
6. Happy Baby Organic Stage 1


Does not contain corn syrup solids, gluten, or GMOs
Is a milk-based powder with prebiotics
Designed for infants with sensitive stomachs
Lactose is reduced by 75% to relieve gas and fussiness
Has four times the prebiotics than other formulas
Some infants had diarrhea with this formula
Constipation was a problem for some
Designed particularly for infants with sensitive stomachs, Happy Baby Organic Stage 1 Infant Formula will relieve gas and fussiness. This is because the lactose included is reduced by 75% compared to other popular brands.
Read moreIngredients
Only great ingredients go into this reflux formula. It does not contain GMOs, gluten, or corn syrup. These are not needed for optimal nutrition in a formula for babies.
Brand
Happy Family Organics intends to change the world, one kid at a time. This company dedicates itself to creating organic, nourishing options that will strengthen children as they grow and change the trajectory of their health. It purchases organic ingredients from local farmers and is a certified B Corp.
Effectiveness
Having 75% less lactose than regular formulas on the market, this diet will reduce the gas and fussiness that most infants experience due to being lactose intolerant.
7. Gerber Good Start


Gentle formula for infant stomachs
Filled with important nutrients for Baby
Contains DHA and Prebiotics as well as protein
Filled with various vitamins and minerals to improve development
Quality control issues; some customers received formula with mold or that was close to/had expired
Gerber isn’t just responsible for that cute little baby with the surprised face and all those mashed peas and carrots. Gerber’s Good Start is a gentle formula meant to aid babies with sensitive little tummies. Fortified with Iron, it contains important nutrients but delivers them in a way that infants might find more digestible.
Read moreIngredients
A blend of DHA, prebiotics, and comfort proteins make up this nurturing formula base. It’s infused with Iron to aid infant's overall development. It also contains multiple vitamins as well as helpful minerals such as Zinc and Manganese, all of which support strong systems.
Brand
Gerber does extensive research into nutrition when they’re making their formulas and food. They strive for the best seeds, the best soil, and thus the best ingredients possible to make up all of the various sustenances that feed your budding family.
Effectiveness
Many parents love this formula and find that their children take it well. For best results, leave the bottle out for a minute or so to let the formula settle after you’ve shaken and mixed it, thus naturally removing air bubbles to lessen the chance of gas.
8. Earth's Best Organic Sensitivity Recipe


DHA and ARA rich formula
No lactose
GMO-free
Iron supplement
Earth’s Best closest formula to breast milk
There is a 2016 lawsuit against the mother company, Hain Celestial, alleging that their products are not Organic, as advertised; do your research if you’re concerned about this
Earth’s Best is an Omega-3 DHA and Omega-6 ARA fatty acid rich formula with reduced lactose and no artificial flavors or colors. It’s made without damaging pesticides and fertilizers, and includes Iron to aid in healthy development.
Read moreIngredients
This particular formula is Earth Best’s closest imitation of breast milk. It cuts the amount of lactose by adding a different, non-milk-based sugar, which will help to ease the digestion in sensitive little tummies. Plus, it’s fortified with important nutrients that aid in red cells, brain, and eye development.
Brand
Earth’s Best strives to promote good food and responsible lifestyles in all kinds of ways. In 2004 they paired with Sesame Street to create the “Healthy Habits for Life” Initiative. The mission of the Koss family has come a long way and continues to work towards new ways to spread the word and all the world’s best ingredients!
Effectiveness
Lots of babies seem to take this anti-reflux formula without much, if any, fuss. It’s engineered to be developmentally beneficial to them, and it’s GMO-free.
9. Similac Sensitive Non-GMO


Makes 28 six ounce bottles
Non-GMO ingredients
Lactose-reduced to ease reflux
OptiGro blend aids in developmental growth
No artificial growth hormones
Some babies still had upset stomachs while using this formula
Caused constipation in some babies
Similac Sensitive Non-GMO is meant for babies with reflux and moms or dads on the hunt for nutrients that haven’t been genetically modified. Currently, the genetically modified ingredients in the baby formula have been approved as harmless, but if you’re concerned about the sources of your ingredients, Similac is your stop.
Read moreIngredients
Their signature OptiGro blend includes DHA (which nourishes the brain), Lutein (for strong eyes), and Vitamin E. All three of these are nutrients found in breast milk which helps to make strong and happy babies. Similac is the top brand picked by both moms and hospitals. It includes no artificial growth hormone, and features the same ingredients as Similac Sensitive, but sourced differently. Similac is one of the most recognizable and recommended names on the market, and it’s no wonder, with over 90 years of dedication to making products that are just right for all kinds of babies.
Brand
Similac is associated with many other brands you may know as well. They’re responsible for Pedialyte and in 1964, Ross Laboratories merged with Abbott Laboratories to create Abbott Nutrition. Similac’s promise is to help support you as you support your baby.
Effectiveness
It’s the same quality ingredients Similac always offers, just sourced differently. This Non-GMO formula for reflux is kind to baby’s stomach, and the brand comes highly recommended by households and hospitals alike.
10. Enfamil Premium Non-GMO Gentlease


Contain DHA and inositol similar to breastmilk
Reduces crying, gas, and fussiness
Contains proteins that are simple to digest
Includes a blend of thirty nutrients
Is a convenient formula already mixed
Some said this is bitter to the taste
A few claim the formula was sour
This Gentlease Formula from Enfamil has been proven to reduce crying, gas, and fussiness within twenty-four hours of feeding.
Read moreIngredients
It contains proteins that are simple to digest because they are broken down partially. For parents who are always on the go, this ready-to-use formula is terrific! It can be fed straight for the nursing bottles that it comes in to make it that more convenient to use.
Brand
Enfamil as you know it has been around since the 1950’s but this brand was born of a father’s need to save his ailing infant sun in 1905 (which he did!), Enfamil wants to be a healthy, happy alternative when your family needs it. Enfamil R was Mead Johnson’s first routinely-administered baby formula, modeled after all of the nutrients and benefits of a mother’s breastmilk. They strive to make products that closely resemble a mother’s milk even today.
Effectiveness
For the problem of reflux, this great formula could help by easing the gas, crying, and fussiness that it creates. It should work within one day of the first feeding.
Criteria Used for Evaluation

Ingredients
Each of these diets is perfect for the whole first year of the baby’s life as a complete nutrition. All of the vitamins and minerals are included to ensure your child is getting all he or she needs for the full requirement of health and happiness. Whether it is a powder to be blended with water or a bottled liquid formula already blended, these are all complete diets perfect to be the sole nutrition for your infant.

Brand
As you will notice, the well-known brands that are so popular today are the ones on this list of best products rated by consumers. This is not a coincidence because they are truly the best that is currently offered online now to reduce or eliminate the problems of fussiness, gas, common reflux, and spit-up in babies. Most of them are a pediatrician, nurse, doctor, or hospital recommended as leading brands in infant nutrition to decrease these issues. You can trust these brand names of Enfamil, Similac, Earth’s Best Organics, Kabrita, Good Sense, The Honest Company, and Happy Baby Organic to provide the best reflux relief formula for your infant.

Effectiveness
Because gas, reflux, and spitting up happens to about half of healthy newborns each year, manufacturers have created these formulas to reduce these conditions. Each one of these products is particularly designed to decrease this problem when feeding the infant. The ingredients that each company uses is slightly different with some of them being organic and some not. Make sure you choose the one that is best suited for your baby. It is mostly a reduction in lactose from cow’s milk that contributes to the reduction of gas and fussiness in babies. These formulas for reflux all have that quality in common.

Commonly known as reflux, babies often have gas or fussiness after they consume their infant formulas. It is technically known as gastroesophageal reflux or GER. What is physically happening in reflux is the food that the baby has in its stomach comes back into the esophagus causing the gas or reflux.
The tube that carries the food to the stomach is known as the esophagus. The valve at the end of the esophagus is not fully developed in babies who suffer from reflux, so it allows the formula to come back up the tube and into the mouth. This valve or muscle should relax normally and close to create a barrier between the stomach and the esophagus to keep the food in the stomach. Once it is fully developed it will do just that. When swallowing, this muscle allows the food to go down into the stomach. It closes when the food is in the stomach.
Reflux is a fairly common problem even in the healthiest of infants and occurs in almost half of all babies in the first few months of life. This problem should end when the child is about a year old. The most common symptom of reflux is spitting up of formula, but other signs could lead to the diagnosis of reflux. Infants could arch their backs right after eating, cough, gag, have trouble swallowing, vomit, wheeze, lose weight, refuse to eat, not eat enough, be fussy, or act colicky.
Besides giving your baby a special formula for reflux, you can try these suggestions to relieve the problem. Holding the baby vertically for about twenty to thirty minutes after feeding will help with digestion. Don’t overfeed the child. It is best to give smaller feedings more often than a few large feedings in a day. After every few ounces of formula, be sure to burp the baby to help the liquid go down and relieve any gas. Adding rice cereal in the mix can also give the formula some substance and help it stay in the stomach and not be regurgitated.
Other Factors to Consider

Value
All of these infant formulas are the top brands chosen by online customers. They have the highest ratings and the most reviews of any products in this category. Consumers overwhelmingly were satisfied with these so much that they would buy them again. We search out the best formulas for reflux to showcase for our buying guides to enhance your shopping experience. For your convenience, we list what customers liked best and the details of the product in a summarized form. In this way, you can make the most informed decisions about the right formula for your baby.

Physical Development
Each of these diets is perfect for the whole first year of the baby’s life as complete nutrition. All of the vitamins and minerals are included to ensure your child is getting all he or she needs for the full requirement of health and happiness. Whether it is a powder to be blended with water or a bottled liquid formula already blended, these anti-reflux formulas are all complete diets perfect to be the sole nutrition for your infant.
Frequently Asked Questions
q: Are all of these powders that must be mixed with water to make a formula?
No, a few of these are liquid formulas that are already mixed and ready to be used. Look at the ones that are in small bottles with about two-ounces to a bottle. Those are the ones that are liquid.
q: Which products have the highest ratings? Which has the most reviews?
Enfamil NeuroPro and Similac sensitive have the highest customer ratings among all the products, and Earth’s Best Organics has the most reviews online from consumers.
q: At what age does reflux begin?
Reflux can begin at day one of an infant’s life and can last for a couple of years. It is basically the intolerance of lactose, which affects plenty of healthy babies born each year.
q: When should spitting up and gas stop when these formulas are used?
Sometimes the problems can be stopped with the first feeding and sometimes it may take a couple of feedings. Within 48 hours, the symptoms should decrease noticeably, or some changes should be apparent in the digestion and stool.
q: Should you still feed the baby this formula if constipation or diarrhea occurs?
No, if these problems occur, then stop using the formula and try something else. You may want to consult a doctor if this happens, so they can recommend a diet that will not cause any of these issues.
q: At what point do you consult a doctor for reflux or gas in a baby?
Always use the recommended formula from your doctor to feed the baby. If the child develops the reflux problem, check with the doctor for recommendations on a formula for reflux. After trying a formula for gas and reflux and it does not work, then consult a doctor. They will be able to recommend a formula that should work for your baby. You should never switch formulas without checking with the doctor first. Frequent switching back and forth of formulas could cause major problems of diarrhea or constipation for the infant. Finding one formula that works that can be used throughout the first year is the goal.
q: What makes these formulas better for common reflux than regular formulas?
The condition of reflux is soothed by a formula that contains less cow’s milk in the form of lactose. Less gas will be present in these diets that are particularly aimed at reducing common reflux. Until the esophagus muscle develops to prevent the backup of the formula in the tube, these formulas can decrease the symptoms of reflux. The Kabrita product is made completely of goat’s milk to combat the gas problem, as it is more gentle on the digestive system than cow’s milk.
q: What are the signs of reflux and how will I know that it is reflux that my baby suffers from?
When your baby spits up its formula after eating, it is most likely reflux from the underdevelopment of the valve muscle in the esophagus. The infant can also exhibit signs of common reflux as gas, fussiness, and frequent crying. Gas and reflux can be a painful or uncomfortable experience for an infant, so they will show signs of distress in these forms.
Sources
- Reflux in Infants, Online Article ,
- Infant reflux, Online Article ,
- Causes of Acid Reflux in Infants, Online Article ,